Devon Rex Health Problems: Symptoms and When to Worry
The most common Devon Rex health problems are hypertrophic cardiomyopathy, devon rex myopathy, and skin conditions. Devon Rexes typically live 9–15 years. This page is organized by symptom, so you can jump straight to heart, skin, joint, and other problems, see what each one looks like in a Devon Rex, and know whether it is a vet visit this week, a vet visit today, or an emergency right now.

Quick answer: when to worry about your Devon Rex
Go to an emergency vet now if you see any of these:
- Heart: Collapse, fainting, blue gums, labored breathing, or sudden hind-leg paralysis with cold legs (a clot) is an emergency.
- Skin and coat: Sudden facial swelling or hives with vomiting or breathing trouble (an allergic reaction), maggots on the skin, or a large burn is an emergency.
- Joint, back, and mobility: Sudden inability to use the back legs, dragging the hindquarters, or crying out when touched along the spine is an emergency. A ruptured disc has a window of hours for the best outcome.
- Other: Collapse, difficulty breathing, uncontrolled bleeding, or severe pain is always an emergency.
- Any pet: collapse, seizures lasting more than five minutes, uncontrolled bleeding, or an inability to stand.
Book a vet visit this week if you see any of these:
- Heart: A murmur your vet has heard, coughing at night, tiring on walks, or a resting breathing rate over 30 breaths per minute while asleep.
- Skin and coat: Persistent itching, hair or quill loss, hot spots, sores, or a smell that does not go away after a bath.
- Joint, back, and mobility: Limping for more than a day or two, stiffness after rest, reluctance to jump or climb stairs, or a change in gait.
- Other: Any change that lasts more than a day or two, or anything that worries you.
Keep watching if: the change is mild, your Devon Rex is still eating, drinking, and moving normally, and it resolves within a day or two. Write down what you saw and when; a dated list is the most useful thing you can bring to a vet.
Heart problems in Devon Rexes
Hypertrophic Cardiomyopathy (HCM)
Devon Rex have an increased incidence of this heart condition that thickens the heart muscle.
How common in Devon Rexes: Higher than average
What it looks like in a Devon Rex:
- Rapid breathing
- Lethargy
- Hiding
- Sudden collapse
Outlook: this is one of the conditions that can shorten a Devon Rex's life. Managed early it is often years, not months, but it belongs on the list of things that eventually lead to end-of-life decisions.
When to see a vet: A murmur your vet has heard, coughing at night, tiring on walks, or a resting breathing rate over 30 breaths per minute while asleep.
When it is an emergency: Collapse, fainting, blue gums, labored breathing, or sudden hind-leg paralysis with cold legs (a clot) is an emergency.
Skin and coat problems in Devon Rexes
Skin Conditions
Their thin coat makes skin conditions more visible and sometimes more problematic.
What it looks like in a Devon Rex:
- Oil buildup
- Dermatitis
- Malassezia infections
When to see a vet: Persistent itching, hair or quill loss, hot spots, sores, or a smell that does not go away after a bath.
When it is an emergency: Sudden facial swelling or hives with vomiting or breathing trouble (an allergic reaction), maggots on the skin, or a large burn is an emergency.
Joint, back, and mobility problems in Devon Rexes
Patellar Luxation
Loose kneecaps more common in this breed.
What it looks like in a Devon Rex:
- Skipping gait
- Leg held up
- Stiffness
When to see a vet: Limping for more than a day or two, stiffness after rest, reluctance to jump or climb stairs, or a change in gait.
When it is an emergency: Sudden inability to use the back legs, dragging the hindquarters, or crying out when touched along the spine is an emergency. A ruptured disc has a window of hours for the best outcome.
Other health problems in Devon Rexes
Devon Rex Myopathy
A hereditary muscle disease specific to Devon Rex causing muscle weakness.
How common in Devon Rexes: Genetic test available
What it looks like in a Devon Rex:
- Head bobbing
- Muscle weakness
- High stepping gait
- Difficulty swallowing
Outlook: this is one of the conditions that can shorten a Devon Rex's life. Managed early it is often years, not months, but it belongs on the list of things that eventually lead to end-of-life decisions.
When to see a vet: Any change that lasts more than a day or two, or anything that worries you.
When it is an emergency: Collapse, difficulty breathing, uncontrolled bleeding, or severe pain is always an emergency.
Warning signs to watch for in a Devon Rex
These are the early signals owners most often miss, or dismiss as age:
- Breathing changes
- Muscle weakness or trembling
- Head bobbing or difficulty eating
- Excessive skin oil or irritation
Devon Rex lifespan: what is normal
Devon Rex typically live 12-15 years with proper care and attention to their specific needs.
Genetic factors
The Devon Rex mutation affects hair structure. Some lines carry genes for heart and muscle conditions.
What Devon Rexes usually die from
Knowing what typically ends a Devon Rex's life is not morbid. It tells you which of the symptoms above deserve the fastest response.
- Heart disease (HCM) (about 30%): Hypertrophic cardiomyopathy.
- Devon Rex Myopathy (about 15%): When inherited.
- Kidney disease (about 20%): Common in older cats.
- Cancer (about 15%): Various cancers.
When it may be time: from managing symptoms to saying goodbye
Some of the conditions above (hypertrophic cardiomyopathy and devon rex myopathy) are managed for years. Each one, though, has a point where treatment prolongs the decline rather than the life. If you are reading this page because your Devon Rex is older and the bad days are starting to outnumber the good, that is worth saying plainly: you may not be looking for a diagnosis anymore. You may be looking for permission.
Signs the balance has shifted in a Devon Rex:
- Rapid or labored breathing
- Muscle weakness
- Less jumping and climbing
- Seeking warmth constantly
The when to say goodbye to your Devon Rex guide walks through the quality-of-life scale vets use, what euthanasia actually involves, and how to prepare. If you are weighing costs and options, the pet end-of-life services guides by city cover in-home euthanasia and cremation prices, and the coping with losing a Devon Rex guide is there for afterward.
Preventive care for Devon Rexes
- Annual echocardiogram for heart screening
- Genetic testing for myopathy
- Regular skin care and ear cleaning
- Warmth-they get cold easily
Sources
This page is compiled from veterinary references and breed-specific health studies. It is general information, not a diagnosis; your vet knows your Devon Rex.
- https://icatcare.org/advice/devon-rex/
- https://www.ufaw.org.uk/cats/devon-rex
If this has stopped being about symptoms
Many people land here when their Devon Rex is old or ill and they are trying to work out whether what they are seeing is the end. If that is you, the health details above matter less than the question underneath them.
Devon Rex Health FAQs
- What are the most common health problems in Devon Rexes?
- The conditions most often seen in Devon Rexes are hypertrophic cardiomyopathy, devon rex myopathy, skin conditions, and patellar luxation. Devon Rex have an increased incidence of this heart condition that thickens the heart muscle.
- What do Devon Rexes usually die from?
- The leading causes of death in Devon Rexes are heart disease, devon rex myopathy, and kidney disease. Hypertrophic cardiomyopathy. Devon Rexes typically live 9–15 years.
- Do Devon Rexes have heart problems?
- Yes. The heart conditions seen in Devon Rexes are hypertrophic cardiomyopathy. A murmur your vet has heard, coughing at night, tiring on walks, or a resting breathing rate over 30 breaths per minute while asleep. Collapse, fainting, blue gums, labored breathing, or sudden hind-leg paralysis with cold legs (a clot) is an emergency.
- Do Devon Rexes have skin problems?
- Yes. The skin conditions seen in Devon Rexes are skin conditions. Persistent itching, hair or quill loss, hot spots, sores, or a smell that does not go away after a bath. Sudden facial swelling or hives with vomiting or breathing trouble (an allergic reaction), maggots on the skin, or a large burn is an emergency.
- At what age do Devon Rexes start having health problems?
- Inherited conditions can show up in the first few years. Age-related problems like arthritis, kidney decline, and cancer cluster in the last third of a Devon Rex's 9–15 years lifespan, so twice-yearly checkups from about 5 years old catch most things early.
- What are the signs a Devon Rex is dying?
- The signs that a Devon Rex is nearing the end are refusing food and water, being unable to stand or get to the bathroom without help, pain that medication no longer reaches, withdrawing from the family, and more bad days than good over two weeks. Our when-to-say-goodbye guide for the Devon Rex walks through the quality-of-life scale vets use and what euthanasia involves.
- How do I know if my Devon Rex is in pain?
- Devon Rexs often hide pain. Watch for: changes in appetite, reluctance to move, unusual posture, excessive licking of one area, withdrawal, aggression when touched, panting (in cats), or changes in sleep patterns. Any significant behavior change warrants a vet visit.
- At what age is a Devon Rex considered senior?
- With a typical lifespan of 9–15 years, Devon Rexs are generally considered senior in the last third of their expected life. Indoor cats tend to age more slowly than outdoor cats. Senior Devon Rexs benefit from more frequent vet visits and age-appropriate nutrition.
Keep their memory close
If you're facing a difficult time, these may bring comfort.